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Global Health

Our Global Health research covers the following research groups: Addressing Chronic Kidney Disease; Cardiovascular Disease; Infections; Injury Prevention and Trauma Care; INTERGROWTH 21st; Multimorbidity; Neurodevelopment; The Oxford Maternal & Perinatal Health Institute (OMPHI); Preventing Childhood Cancer; (International Childhood Cancer Cohort Consortium and Childhood Determinants of Adult Health Study); SMARThealth Pregnancy: Improving women’s life-long health in rural India; Women’s Health and Sex Inequalities; Urban Health and a Zika Online Data Sharing Platform.

Smarthealth pregnancy 1


Topics in this theme

2.6 million people in England currently live with chronic kidney disease (CKD), a long-term, irreversible condition in which the kidneys do not work as well as they should to clean the blood, and makes individuals more susceptible to advanced stages of the disease at times when they may be unwell for other reasons. Those individuals with severely limited kidney function also have an increased risk of hospital admission and death.
Addressing Chronic Kidney Disease
Cardiovascular diseases are the leading cause of death in the world. The work of this research group integrates large databases of electronic health records, clinical trials, meta-analyses and digital technologies to better understand the determinants and consequences of cardiovascular disease, and how to improve quality of care and health outcomes.
Cardiovascular Disease
The Childhood Determinants of Adult Health (CDAH) Study is a cohort study with follow-up of 8,498 children who participated in the 1985 Australian Schools Health and Fitness Survey (ASHFS) when aged 7 to 15 years.
Childhood Determinants of Adult Health Study (CDAH)
How understanding the immunological status of HIV-infected pregnant women can help to identify which women are most likely to have babies born too early or too small, and support the development of novel preventative and therapeutic interventions.
Infections
Each year, 10% of deaths worldwide are the result of injuries and violence, amounting to more than 5.8 million people. However, this global epidemic is poorly recognised, with weak investment in effective preventative programmes and patchy provision of accessible and appropriate care for those affected.
Injury Prevention and Trauma Care
An International Fetal and Newborn Growth Consortium dedicated to improving perinatal health through the development of new fetal and newborn growth standards, providing tools for the continuity of care from conception to 5 years of age.
INTERGROWTH-21st
The International Childhood Cancer Cohort Consortium (I4C) is the world’s largest study into childhood cancer, and looks specifically at preventable causes.
International Childhood Cancer Cohort Consortium (I4C)
Recent advances in medicine and health policy have led to an unprecedented increase in life expectancy. This longevity has also seen an increasing number of people, particularly older adults, suffering from two or more serious chronic diseases - a status known as multimorbidity.
Multimorbidity
Evaluating neurodevelopment in different cultural settings is an integral component of early child development and is essential for observational and interventional studies focused on the first 1000 days of life.
Neurodevelopment
The Oxford Maternal & Perinatal Health Institute (OMPHI) works alongside Nuffield Department of Women's & Reproductive Health - bringing together world experts to resolve priority maternal and perinatal health problems on a global scale.
Oxford Maternal & Perinatal Health Institute (OMPHI)
Childhood cancer is one of the major causes of death and serious illness in children, with almost 300,000 children developing cancer each year around the and an estimated 80,000 deaths annually. While many children in high-income countries are successfully treated, in many low- and middle-income countries, only 20% of children survive.
Preventing Childhood Cancer
Every year, millions of women die from heart disease, stroke and complications of diabetes, with the greatest number of deaths occurring in low-resource settings, such as parts of rural India. Dr Jane Hirst and Dr D Praveen lead the SMARThealth Pregnancy programme, which aims to help community health workers identify women at risk and manage their healthcare in order to reduce premature deaths
SMARThealth Pregnancy: Improving women’s life-long health in rural India
Today, over 55% of the world’s population live in urban areas, with growth expected to accelerate in low-income and lower-middle-income countries over the next three decades. In order that this urbanisation is inclusive, safe and sustainable, it must be carefully managed to ensure that city spaces are ready to cater for the health of their expanding communities, and that of future citizens.
Urban Health
Women’s health is frequently considered in terms of birthing and childcare. However, this grossly misrepresents the reality of women’s health experiences and needs. Non-communicable diseases and injury impose an enormous burden on women. Although there is considerable evidence of women being undertreated or presenting disease in a different way to men, sex-specific analyses of clinical trials and epidemiological studies are by no means universal.
Women’s Health and Sex Inequalities
The Nuffield Department of Women's & Reproductive Health leads a multi-disciplinary team of clinician scientists, epidemiologists, geneticists, engineers, computational biologists and radiologists from Brazil, the USA and UK, to produce an online, digital information platform for images of fetal and newborn heads (plus associated clinical records) as a global data-sharing resource.
Zika Online Data-sharing Platform