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Cancer

Our Cancer research covers the following research groups: Cervical Neoplasia (developing therapeutics to eradicate HPV infections in women), Nanoparticles in Cancer (focussing on the use of nanoparticles in cancer for therapy, imaging or drug delivery) and Ovarian Cancer (exploring the molecular mechanisms that drive Ovarian Cancer cell growth and examining which targeted therapies can be utilised to improve treatment).

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Topics in this theme

Cervical Neoplasia
Cervical Neoplasia
Our research focuses on the use of nanoparticles in cancer for therapy, imaging or drug delivery.
Nanoparticles in Cancer
Ovarian cancer is one of the most lethal gynaecological malignancies predominantly because of late presentation and chemotherapy resistance. Recent advances in single cell RNA sequencing and DNA sequencing have made it possible to obtain unprecedented insights into tumour biology. Our lab has developed sequencing strategies and analysis algorithms to accelerate the mechanistic understanding of ovarian cancer initiation, progression and chemotherapy resistance. The use of these technologies and our access to patients recruited in clinical research studies provide exciting opportunities for addressing key questions in ovarian cancer such as a) understanding the cell of origin of ovarian cancer, b) characterising the tumour initiating cells in minimal residual disease and c) understanding T cell immune responses against ovarian cancer initiation and progression.
Ovarian Cancer