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Ana Kisovar


Postdoctoral Research Assistant in Bioinformatics / Immunology

I am a medical doctor from Slovenia. After graduating from the Faculty of Medicine in Ljubljana (Slovenia) and the University of Heidelberg (Germany) in 2019, I completed my clinical training and worked as a medical writer in Zurich (Switzerland) before starting my DPhil at the Nuffield Department of Women's and Reproductive Health in 2020.

Under the supervision of Dr. Jen Southcombe, Assoc. Prof. Ingrid Granne, and Assoc. Prof. Christian Becker, my research delved into the immunological background of adverse reproductive outcomes, including recurrent pregnancy loss and endometriosis-associated subfertility. Endometriosis, defined as the growth of endometrium-like tissue outside the uterus, affects 1 in 10 women, of whom 35–50% suffer from subfertility. Recurrent pregnancy loss is defined as the loss of two or more subsequent clinically recognized pregnancies before week 24 and affects 1 in 50 pregnant women. In my thesis, I investigated the role of CD8+ T cells, the major T cell population, constituting 25–35% of all endometrial leukocytes.

Drawing on my clinical and research expertise, I am currently undertaking single-cell RNA sequencing to better define and understand endometrial adaptive immunity during the window of embryo implantation. This will hopefully lead to new ways to treat recurrent pregnancy loss and endometriosis-associated subfertility.

Recent publications

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