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PROJECT TITLE

Understanding the mechanisms underpinning the disease symptoms of endometriosis and adenomyosis.

SUPERVISORS

Dr Jen Southcombe

Professor Christian Becker

Dr Rebecca Dragovic

To discuss project options, please email endocare@wrh.ox.ac.uk detailing your specific research interests and attach a copy of your CV.  

DESCRIPTION OF PROJECT

As part of EndometriosisCaRe Oxford https://www.wrh.ox.ac.uk/research/endometriosis-care you will work to advance our knowledge of endometriosis and/or adenomyosis lesion progression. 

Projects are welcome across various avenues of research, which could include:

  • Histological analysis of the cellular composition of endometriosis lesions, studying the differences between lesion types.
  • Human organoid models for the analysis of eutopic epithelium cell growth and drug treatment options.
  • Inflammation and cellular immunity in endometriosis.
  • Extracellular vesicles (EVs) in the pathogenesis of endometriosis.

 

Training opportunities

You will be trained in a wide variety of laboratory techniques: flow cytometry, specific EV analysis techniques such as Nanoparticle Tracking Analysis (NTA), tissue culture, western blotting, IHC including fluorescence and confocal microscopy, PCR and RT-PCR, sequencing transcriptome analysis, ELISA.

There will be opportunities to present work within the department, and at national & international conferences. Students are encouraged to prepare and submit manuscripts.

As well as the specific training detailed above, students will have access to a wide-range of seminars and training opportunities within the University of Oxford network.

 

 Funding

Successful candidates will be supported with their applications for independent funding for course fees, etc.  Lab consumables are provided, please approach the supervisor team to discuss project opportunities.

 

HOW TO APPLY

To apply for this research degree, please click here.