Dr Karin Hellner
Clinical Referrals
For NHS and clinical queries please contact my secretary Charlotte Whipp on 01865 234453 or email charlotte.whipp@ouh.nhs.uk. For colposcopy related enquiries please contact the Colposcopy Department on 01865 572110 or email orh-tr.colposcopyoxford@nhs.net.
For private patient appointments please contact my secretary Janet White via oxfordcolposcopy@gmail.com.
Clinical Trials
We are carrying out a number of research studies to help us design and test new treatments for cervical abnormalities caused by infection with oncogenic HPV.
HPV Vaccine Trial
REVEAL-01 is investigating the first therapeutic vaccine to show efficacy against cervical abnormalities associated with HPV-16 and HPV-18. Its predecessor trial was published in the Lancet in 2015, indicating the vaccine could present a non-surgical option to treat CIN2/3. REVEAL-01 is a randomised, double-blind, placebo-controlled study involving 200 sites worldwide.
HPV Immunity study
This trial aims to find out how the immune system clears high-risk HPV, the viruses that cause cervical cancer (http://www.jenner.ac.uk/hpvhttp://www.jenner.ac.uk/hpv). We are looking for women aged 16-24 years who are in good health. If you are interested, please contact the research team on hpv-study@ndm.ox.ac.uk.
Karin Hellner
MD PhD
Senior Fellow in Women's Health
- Consultant Gynaecologist and Colposcopist at Oxford University Hospitals NHS Foundation Trust
- Clinical Lead for Colposcopy
- Principal Investigator
- BSCCP Representative for South-East England
- Lead for OUH Cervical Sample Taker Register
- PI for REVEAL-01 Trial
Biography & Research
I received my medical degree from the Humboldt-University of Berlin in 2003 and split my specialist training in Obstetrics & Gynaecology between the Charité - Universitätsmedizin Berlin, in Germany, and Oxford University Hospitals NHS Foundation Trust, in Oxford, UK.
I spent 4 years as a postdoctoral research fellow at Harvard Medical School / Brigham & Women's Hospital in Boston, USA, where I have been working on the molecular mechanisms of human papillomavirus (HPV) associated carcinogenesis and drug discovery strategies for cervical cancer.
I joined the University of Oxford in 2011 as a Clinical Lecturer and was appointed as Senior Fellow in Women's Health in 2017.
I have a strong clinical interest in HPV associated cervical disease and am leading a research program in the field of the molecular basis and clinical management of cervical dysplasia. I am the lead consultant for Oxford's colposcopy service and Principal Investigator of multiple national and international clinical trials.
In addition, I am a board member of the British Society for Colposcopy and Cervical Pathology (BSCCP) representing the South-East of England, a BSCCP accredited colposcopy trainer and elected member of the Society for Reproductive Investigation (SRI). In my spare time I volunteer as expert reviewer for Jo's Cervical Cancer Trust Charity.
Fellowships & Awards
- 2000 - 2001: PhD student fellowship by the Charite - Medical Faculty, Humboldt-University of Berlin
- 2007 - 2008: Postdoctoral Research Fellowship by the German Research Foundation (DFG) for basic research at Harvard Medical School Boston, USA
- 2010: DNA Tumor Virus Conference Grant
- 2010: Brigham & Women's Hospital Peer Mentor Award
- 2015: Oxford University Clinical Academic Graduate School (OUCAGS) Career Development Grant
- 2015: OUCAGS Travel Grant for Clinical Lecturers
- 2017: Bayer Grants4Targets Award
Key publications
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Journal article
Hancock G. et al, (2018), Best Practice & Research Clinical Obstetrics & Gynaecology, 47, 59 - 72
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Journal article
Hellner K. and Dorrell L., (2017), F1000Research, 6, 269 - 269
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Journal article
Rahmioglu N. et al, (2017), Epigenetics, 12, 897 - 908
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Journal article
Hellner K. and Münger K., (2011), Journal of Clinical Oncology, 29, 1785 - 1794
Recent publications
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Journal article
Zheng Y. et al, (2018), Nature Communications, 9
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Peripheral Basophil Count is Increased in Patients with Endometriosis.
Conference paper
Feng Q. et al, (2018), REPRODUCTIVE SCIENCES, 25, 218A - 218A
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Journal article
Hancock G. et al, (2018), Best Practice & Research Clinical Obstetrics & Gynaecology, 47, 59 - 72
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Journal article
Rahmioglu N. et al, (2017), Epigenetics, 12, 897 - 908
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Journal article
Taylor C. et al, (2017), Oncotarget, 8
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Journal article
Hellner K. and Dorrell L., (2017), F1000Research, 6, 269 - 269
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The Predictive Potential of Peripheral Blood Basophils in Endometriosis.
Conference paper
Guan J. et al, (2017), REPRODUCTIVE SCIENCES, 24, 207A - 207A
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Journal article
Hellner K. et al, (2016), EBioMedicine, 10, 137 - 149
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Evaluation Of the Monocyte To Lymphocyte Ratio As a Predictive Marker in Endometriosis Patients.
Conference paper
Hellner K. et al, (2016), REPRODUCTIVE SCIENCES, 23, 327A - 327A
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Journal article
Gulbahce N. et al, (2012), PLoS Computational Biology, 8, e1002531 - e1002531