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Join the PURE - FIRST Study

Enhancing Early Detection of Fetal Conditions

Email us to join the study

Why is this Study Important?

In the UK, pregnant women are offered two scans during their pregnancy: one at 11-14 weeks and another at 18-20 weeks gestation. The current medical guidelines emphasise fetal anatomical screening during the second scan. However, emerging evidence, including a comprehensive meta-analysis conducted by our research group, suggests that early assessment of the baby’s anatomy may be possible with the right technology.

The Value of 3D Ultrasound

Adding 3D ultrasound to early pregnancy scans offers significant clinical benefits:

  • Quick Acquisition: A 3D volume can be captured within minutes, allowing for efficient examination.
  • Enhanced Views: 2D image slices within the 3D volume can be manipulated to obtain the best possible views, even when the fetus is not ideally positioned.
  • Major Anatomical Structures: Detailed visualization of major anatomical structures in the first trimester can potentially reduce the time needed to capture these critical images.
  • Sonographer Health: By reducing the need for repeated pressure or maintaining awkward transducer positions, 3D ultrasound can help prevent repetitive strain injuries among sonographers.

About the PURE - FIRST Study

The PURE - FIRST study aims to build on our successful feasibility study by recruiting an additional 300 participants. Our goal is to explore the usability of 3D ultrasound in acquiring a standardised set of 2D images for examining fetal structures between 11-14 weeks gestation.

This research holds the promise of enhancing diagnosis and enabling earlier detection of fetal conditions, benefiting both expectant mothers and healthcare professionals.

Our Clinical Research Group (CRG) are currently recruiting volunteers and collecting data for the study. The research is conducted by Prof. Papageorghiou and his team. 

The team

  • Aris Papageorghiou
    Aris Papageorghiou

    Professor of Fetal Medicine and Director of Research of the Oxford Maternal and Perinatal Health Institute (OMPHI).

How you can help

We are looking for volunteers to participate in this groundbreaking study. By joining, you will contribute to important research that could improve prenatal care and early anomaly detection for future generations.

To volunteer or learn more about the PURE - FIRST study, please contact us (link below). 

Join us in our mission to enhance early detection of fetal anomalies through advanced ultrasound technology. Your involvement is crucial in shaping the future of prenatal care.

Sign-up today

By volunteering in medical research, you contribute to advancements that can improve countless lives and become a part of groundbreaking discoveries. Your efforts can spark change and inspire others, creating a ripple effect of positive impact. - Professor Krina Zondervan, Head of Nuffield Dept. of Women's & Reproductive Health