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The gene encoding a 90 kDa diacylglycerol kinase protein, DAGK3, that is predominately expressed in the retina, was localised by fluorescence in situ hybridisation to human chromosome 3q27-28. This was subsequently confirmed by mapping of its mouse homologue to chromosome 16, a region syntenic to this part of human chromosome 3. No retinopathies have so far been assigned to this region.

Original publication

DOI

10.3109/02713689508998528

Type

Journal article

Journal

Curr Eye Res

Publication Date

11/1995

Volume

14

Pages

1041 - 1043

Keywords

Animals, Blotting, Southern, Chromosome Mapping, Chromosomes, Human, Pair 3, DNA, Diacylglycerol Kinase, Female, Humans, In Situ Hybridization, Fluorescence, Karyotyping, Male, Mice, Mice, Inbred C57BL, Phosphotransferases (Alcohol Group Acceptor), Retina, Sequence Homology, Nucleic Acid