Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

The sperm activates the egg to begin developing into an embryo by triggering a wave of intracellular calcium release, which sweeps across the egg like a forest fire. The identity of the signaling molecules that mediate this fundamental event has remained a mystery until recently. Now, new information emerging from the genome projects has made it possible to isolate and characterize the proteins responsible.


Journal article


Biologist (London)

Publication Date





5 - 10


Animals, Calcium Signaling, Female, Fertilization, Fertilization in Vitro, Humans, Male, Ovum, Parthenogenesis, Sperm-Ovum Interactions, Spermatozoa