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The physical and psychological impact of miscarriage can be devastating. There are many lifestyle and therapeutic interventions that may prevent a miscarriage. In this review, we have outlined the key areas for health optimization to prevent pregnancy loss, drawing on the most up-to-date evidence available. The 3 key areas identified are lifestyle optimization in women, lifestyle optimization in men, and therapeutic interventions. The evidence demonstrates that the treatments to consider are first-trimester progesterone administration, levothyroxine in women with subclinical hypothyroidism, and the combination of aspirin and heparin in women with antiphospholipid antibodies.

Original publication

DOI

10.1016/j.fertnstert.2023.08.955

Type

Journal article

Journal

Fertil Steril

Publication Date

11/2023

Volume

120

Pages

951 - 954

Keywords

Interventions, miscarriage, pregnancy loss, Pregnancy, Female, Humans, Abortion, Spontaneous, Abortion, Habitual, Aspirin, Heparin, Thyroxine, Hypothyroidism