Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Ovarian stimulation commonly results in the generation of more embryos than are necessary for the fresh embryo transfer. erefore, cryopreservation and subsequent replacement of frozen-thawed embryos is an integral part of assisted reproductive technology (ART) programs. Frozen embryo replacement (FER) cycles contribute to around 25% of all ART births (1). FER clinical pregnancy rates (CPRs) vary widely. is is at least in part because clinics have varying protocols as to the quality of embryos suitable for cryopreservation, the day of development at which the embryo is frozen, and the technique (slow freezing or vitrification) used. Blastocyst vitrication is now being used more extensively since its widespread introduction over a decade ago (2). As much of the evidence used to guide practice currently is derived from studies using slow freezing, practice will change with increasing evidence from vitrication studies.



Book title

Textbook of Assisted Reproductive Techniques, Fifth Edition: Two Volume Set

Publication Date



732 - 738