Endometriosis – a painful disease

Coxon L., Evans E., Vincent K.

Purpose of review This review looks to overview advances in endometriosis-associated pain, both in understanding the pain mechanisms involved and increasing treatment options with well designed clinical trials and meta-analyses. Recent findings Our understanding of endometriosis-associated pain has progressed from a purely nociceptive model to an awareness that both neuropathic and nociplastic mechanisms can be present for some people with endometriosis. Clinical trials and meta-analyses have demonstrated efficacy of surgical treatments and hormonal therapies. It is notable that currently, the basic science and clinical trials are not cross-fertilising. Summary Following growth in other areas of chronic pain, there have been significant advances in our understanding of endometriosis-associated pain. However, there remains lots to explore and we are currently a long way from our goal of timely personalized holistic multidisciplinary treatment for all sufferers of endometriosis-associated pain.

DOI

10.1097/aco.0000000000001305

Type

Journal article

Journal

Current Opinion in Anaesthesiology

Publisher

Ovid Technologies (Wolters Kluwer Health)

Publication Date

10/2023

Volume

36

Pages

595 - 601

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