Fetal cerebral Doppler changes and outcome in late preterm fetal growth restriction: prospective cohort study.
Stampalija T., Thornton J., Marlow N., Napolitano R., Bhide A., Pickles T., Bilardo CM., Gordijn SJ., Gyselaers W., Valensise H., Hecher K., Sande RK., Lindgren P., Bergman E., Arabin B., Breeze AC., Wee L., Ganzevoort W., Richter J., Berger A., Brodszki J., Derks J., Mecacci F., Maruotti GM., Myklestad K., Lobmaier SM., Prefumo F., Klaritsch P., Calda P., Ebbing C., Frusca T., Raio L., Visser GHA., Krofta L., Cetin I., Ferrazzi E., Cesari E., Wolf H., Lees CC., TRUFFLE-2 Group None.
OBJECTIVES: To explore the association between fetal umbilical and middle cerebral artery (MCA) Doppler abnormalities and outcome in late preterm pregnancies at risk of fetal growth restriction. METHODS: This was a prospective cohort study of singleton pregnancies at risk of fetal growth restriction at 32 + 0 to 36 + 6 weeks of gestation, enrolled in 33 European centers between 2017 and 2018, in which umbilical and fetal MCA Doppler velocimetry was performed. Pregnancies were considered at risk of fetal growth restriction if they had estimated fetal weight and/or abdominal circumference (AC)