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Mitochondria have their own DNA which is maternally inherited. Mitochondrial DNA (mtDNA) diseases are extremely variable because of the genetics of mtDNA and the unique pathogenesis of these disorders. This makes predicting the prognosis and transmission of these disorders difficult.

Type

Journal article

Publication Date

1996-06-05T00:00:00+00:00

Volume

55

Pages

712 - 716

Total pages

4

Keywords

DNA, Mitochondrial, Gene Rearrangement, Humans, Mitochondrial Myopathies, Point Mutation, Prenatal Diagnosis, Prognosis