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We have previously shown that the functional melanoma risk variant rs12203592 in interferon regulatory factor-4 (IRF4) was associated with increased Breslow thickness, an important prognostic indicator for melanoma. In line with this, a recent study found evidence for an association between the minor T allele of this single nucleotide polymorphism (SNP) and melanoma-specific survival in patients from two European hospitals.

Original publication

DOI

10.1111/bjd.18881

Type

Journal article

Journal

Br J Dermatol

Publication Date

20/01/2020