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To the Editor: We are concerned that the study of MacMahon et al. (Feb. 6 issue),* although admirable in design, may have certain methodologic flaws. We doubt that reliable or reproducible M-mode measurements in an obese population can be made to fractions of a millimeter. It seems doubtful that M mode allows detection of a change from, say, 8.5 to 7.6 mm in the thickness of the posterior wall, or from 8.5 to 8.3 mm in the same structure (these numbers are from the authors' Table 2). In the obese, definition of the posterior wall and septum is simply not. © 1986, Massachusetts Medical Society. All rights reserved.

Original publication




Journal article


New England Journal of Medicine

Publication Date