Please join us for this all-day event on Wednesday 2nd December, 9.30am in the Academic Centre, Level 3, John Radcliffe Hospital, Oxford, OX3 9DU. See directions and map.
The registration fee is £10 or £5 (concessions for students and retired academics)
IMPORTANT: The last date for registration is Wednesday 25th November. Register here
The full programme of speakers and topics is as follows:
Session 1 Cancer & Metabolism (Chair: Lisa Heather (DPAG, Oxford)
09.30 Introduction/Welcome by Karl Morten (University of Oxford)
09.35 Karl Morten - (University of Oxford) The Warburg effect: fact, fiction or something else.
09.55 Nivea Amoeda (University of Bordeaux) - The energy requirement of metastatic cells
10.10 Luke Thomas (University of Cambridge) -The role of mitochondria in regulating the hypoxia response.
10.25 Giolio Laurenti (University of Birmingham) - Reduced succinate dehydrogenase activity in gliomas correlates with the activation of the NRF2 pathway.
10.40 Rodrique Rossignol (University of Bordeaux) - Metabolic remodeling in human diseases
11.10 Coffee & Posters
Session 2 Disease I (Chair:Heather Mortiboys, Sheffield)
11.40 Duncan Howie (University of Oxford) - Mitochondria and immune regulation.
12.00 Lynne Cox (University of Oxford) - Nuclease EXDL2 localises to mitochondria and is required for cell viability.
12.15 Hanne Hoitzing or Juvid Aryaman (Imperial College,London) - What is the function of mitochondrial networks? A theoretical assessment of hypotheses and proposal for future research.
- Modelling the cell physiological effects of MELAS across the spectrum of heteroplasmic load
12.30 Alastair Nunn - Quantum hormesis and the mitochondrion; from thermal vents to cognition
12.45 Letizia Lo Faro (University of Oxford)- Targeting metabolic pathways in brain dead donors to improve outcomes of kidney transplantation
12.55 Phillip West (Yale/SMUDallas) - Mitochondria and innate immunity. Sponsored by the Biochemical Society
13.25 Lunch by Spice Indira & Posters
Session 3 Mitochondrial Biology (Chair: Joanna Poulton, NDOG, Oxford)
14.30 Massimo Zeviani (MBU, Cambridge University) - New mechanisms of neurodegeneration in mitochondrial disorders
15.00 Carlo Viscomi (MBU, Cambridge University) - Models of mitochondrial disease
15.20 Nuno Raimundo (University of Goettingen) - Cross-talk between mitochondria and lysosomes regulates cellular signalling and pathology onset.
15.35 Michelangelo Campanella (Royal Vet College/UCL) - Cell mitophagy regulation in health and disease.
15.55 Poulton/Diot (University of Oxford) - Modulating mitochondrial quality control in disease transmission: towards enabling mitochondrial DNA disease carriers to have healthy children
16.10 Tea/Coffee & Posters
Session 4 Disease II (Brent Ryan, DPAG, Oxford)
16.40 Tamara Sirey (University of Oxford) - Non-coding RNA regulation of complex I
17.00 Wei Huang (Oxford, Engineering) - Label-free detection of single cell phenotype using Raman micro-spectroscopy
17.15 Andrei Tarasov (University of Oxford)- Paradoxical posthyperglycaemic stimulation of oxidative metabolism in pancreatic islets.
17.30 Stefania Monterisi (University of Oxford) PDE2A shapes a cAMP/PKA microdomain at the mitochondria with effects on mitochondria morphology and cell survival.
17.45 Drinks & Nibbles
19.30 MitOX Dinner