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The Nuffield Department of Obstetrics & Gynaecology (NDOG) invites you to MitOX - one of the best annual Mitochondrial meetings in the UK on Wednesday 2nd December.

Please join us for this all-day event on Wednesday 2nd December, 9.30am in the Academic Centre, Level 3, John Radcliffe Hospital, Oxford, OX3 9DU. See directions and map.

The registration fee is £10 or £5 (concessions for students and retired academics) 

IMPORTANT: The last date for registration is Wednesday 25th November. Register here

The full programme of speakers and topics is as follows: 

Session 1  Cancer & Metabolism (Chair: Lisa Heather (DPAG, Oxford)

09.00        Registration

09.30        Introduction/Welcome by Karl Morten (University of Oxford) 

09.35        Karl Morten - (University of Oxford) The Warburg effect: fact, fiction or something else.

09.55        Nivea Amoeda (University of Bordeaux) - The energy requirement of metastatic cells

10.10        Luke Thomas (University of Cambridge) -The role of mitochondria in regulating the hypoxia response.

10.25        Giolio Laurenti (University of Birmingham) - Reduced succinate dehydrogenase activity in gliomas correlates with the activation of the  NRF2 pathway.

10.40         Rodrique Rossignol (University of Bordeaux) - Metabolic remodeling in human diseases

11.10         Coffee & Posters

Session 2 Disease I (Chair:Heather Mortiboys, Sheffield)

11.40         Duncan Howie (University of Oxford) - Mitochondria and immune regulation. 

12.00         Lynne Cox (University of Oxford) - Nuclease EXDL2 localises to   mitochondria and is required for cell viability.

12.15         Hanne Hoitzing or Juvid Aryaman (Imperial College,London) - What is the function of mitochondrial networks? A theoretical assessment of hypotheses and proposal for future research.

- Modelling the cell physiological effects of MELAS across the spectrum of heteroplasmic load

12.30         Alastair Nunn - Quantum hormesis and the mitochondrion; from thermal vents to cognition

12.45         Letizia Lo Faro (University of Oxford)- Targeting metabolic pathways in brain dead  donors to improve outcomes of kidney transplantation

12.55         Phillip West (Yale/SMUDallas) - Mitochondria and innate immunity. Sponsored by the Biochemical Society

Biochemical logo

13.25         Lunch by Spice Indira & Posters


Session 3   Mitochondrial Biology (Chair: Joanna Poulton, NDOG, Oxford)

14.30    Massimo Zeviani (MBU, Cambridge University) - New mechanisms of  neurodegeneration in mitochondrial disorders

15.00    Carlo Viscomi (MBU, Cambridge University) - Models of mitochondrial disease

15.20    Nuno Raimundo (University of Goettingen) - Cross-talk between mitochondria and lysosomes regulates cellular signalling and pathology onset.

15.35    Michelangelo Campanella (Royal Vet College/UCL) - Cell mitophagy regulation in health and disease.

15.55         Poulton/Diot (University of Oxford) - Modulating mitochondrial quality control in disease transmission: towards enabling mitochondrial DNA disease carriers to have healthy children

16.10         Tea/Coffee & Posters

Session 4 Disease II (Brent Ryan, DPAG, Oxford)

16.40         Tamara Sirey (University of Oxford) - Non-coding RNA regulation of complex I

17.00         Wei Huang (Oxford, Engineering) - Label-free detection of single cell phenotype using Raman micro-spectroscopy

17.15         Andrei Tarasov (University of Oxford)- Paradoxical posthyperglycaemic stimulation of oxidative metabolism in pancreatic islets.

17.30         Stefania Monterisi (University of Oxford) PDE2A shapes a cAMP/PKA microdomain at the mitochondria with effects on mitochondria morphology and cell survival.

17.45         Drinks & Nibbles

19.30         MitOX Dinner

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