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The Nuffield Department of Women's & Reproductive Health invites you to MitOX 2022 on Friday 8th April. Our annual conference for researchers with an interest in mitochondria from academia and pharma. This year's event will be 'hybrid', so you can join in-person or virtually!

Digital illustration of Mitochondria

ABOUT MITOX

The Nuffield Department of Women's & Reproductive Health invites you to MitOX 2022 on Friday 8th April 2022. It's our annual meeting packed with short talks and posters on cancer metabolism, neuroscience, diabetes, mitochondrial disorders and general mitochondrial biology. This one day hybrid conference is ideal for researchers with an interest in mitochondria from both academia and pharma. It will include a range of short talks and posters on cancer metabolism, neuroscience, diabetes, mitochondrial disorders and general mitochondrial biology.  

 

Download the full programme here.

HOW TO BOOK

Book online here.

Face to face registration is now open with a £30 registration fee. Please note that those wishing to present a poster need to register for the face to face meeting. If you have previously registered for online-only option, please feel free to register for the face event if you wish to do so.

We are currently limited on in-person numbers to 58 people.

 The online-only attendance option is free of charge.

Venue: This event will be hybrid. It will take place on Zoom and in-person attendance will take place in the Academic Block at the John Radcliffe Hospital, Oxford OX3 9DU. See directions and map.

The last booking date for this event is TBC.

For all conference enquiries, please contact ndwrhmitox@wrh.ox.ac.uk

Abstracts

Please submit abstracts to be considered  for short  talks and posters to Danielle Hoare at danielle.hoare@wrh.ox.ac.uk

In the E-mail please use 'Abstract for MitOX 2022as the subject line and kindly state if you wish to be considered for a talk only, poster only or either a talk or a poster.

Abstracts should be a standard  conference format on a single side of A4.

The deadline for abstracts is the 20th March 2022.

 

SPEAKERS 

 

Time

Speaker

Title of talk

09.00am

Karl Morten, University of Oxford

Welcome 

09.05am

Chair: Jo Poulton, University of Oxford

First Session: Mitochondrial DNA, expression and recombination

09.05am

Dan Mishmar, Ben Gurion University, Israel

The impact of mitochondrial gene expression regulation, and its coordination with the nucleus, on disease

09.30am

Ana Victoria Lechuga-Vieco, University of Oxford

Mitochondrial heterogeneity: friend or foe?.

09.55am

Yizhou Yu, Cambridge

Parp mutations protect from mitochondrial toxicity in Alzheimer’s disease

10.10am

Hansong Ma, University of Cambridge

Mitochondrial recombination reveals genetic interactions that modulate the phenotypic expression of pathogenic mtDNA mutants

10.35am

Coffee Break

 

11.00am

Chair: Rhiannon McGeehan, University of Portsmouth

Second Session: Cancer

11.00am

Payam Gammage, Glasgow

The impact of cancer-associated mtDNA mutations on tumour metabolism and the microenvironment

11.25am

Markus Ralser, The Francis Crick

Institute, MRC

The metabolic growth limitations of petite cells lacking the mitochondrial genome

11.50am

Nuno Santos Leal, University of Cambridge

Contacts between mitochondria and the endoplasmic reticulum protect from mitochondrial toxicity by activating the PERK/ATF4 branch of ER stress 

12.05pm

Mike Duchen, UCL

Rewiring cell signalling pathways in pathogenic mtDNA mutations

12.30pm

Sponsors Talks   BMG Labtech, Promega, Agilent, Atlantic imaging

 

13.00pm

Lunch and Poster Session I

 

14.00pm

Katharina  Schlacher, Houston, USA

BRCA/FANC tumor suppressor roles in mitochondrial genome instability and inflammation

14.25pm

Chair: Tom Nichol, University of Oxford)

Third Session; Mitophagy and Dynamics

14.25pm

Pollard Lecture William Mair (Harvard) 

Metabolic Flexibility, Mitochondrial Dynamics & Healthy Aging

15.05pm

Brent Ryan, University of Oxford 

Integrating animal and cellular models to understand mitochondrial dysfunction in Parkinson’s disease

15.20pm

Tea & Poster Session II  

 

16.00pm

Chair: Kerstin Timm, University of Oxford

Fourth Session: Mitochondrial medicine

16.00pm

Leanne Hodson, University of Oxford

Tracing fat to determine factors influencing mitochondrial fatty acid oxidation in human

16.25pm

Lisa Heather, University of  Oxford

Diabetic cardiac mitochondria are resistant to the regulation of respiration by lipid intermediates

16.50pm

Robin Klemm, University of Oxford

Mechanisms controlling de novo lipogenesis based lipid droplet expansion during adiopcyte differentiation

17.15pm

Isabella Panfoli, Genova

The polyphenol Cirsiliol prevents the light-induced oxidative damage of the retinal rod outer segment in vitro

17.30pm

Close & Poster Prizes

 

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