In this Q&A, Dr Eszter Dombi reflects on her journey through NDWRH, the mentors and collaborations that shaped her path, and how her time at Oxford continues to influence her work today.
1. Please tell us about your educational journey in women’s health?
I began my educational journey in women's health in 2015, when I had the opportunity to join the Mitochondrial Genetics Group under the mentorship of Professor Joanna Poulton as a DPhil student. During my time with the group, I focused on mitochondrial quality control and investigated how its modulation could be exploited as a potential treatment for mitochondrial diseases.
Following the completion of my DPhil and first postdoc project at the Nuffield Department of Women's & Reproductive Health (NDWRH) I moved to the United States to work on mitochondrial DNA fork protection defects in Fanconi Anaemia at MD Anderson Cancer Center in Houston, Texas. In 2022, I returned to Oxford, where I currently reside.
2. Who were some of the key department members that influenced you during your studies?
During my studies, I was fortunate to be part of this highly collaborative department that brought together multiple research groups working across various aspects of women's health. This environment fostered a deep sense of support and teamwork, which greatly influenced my growth. I was particularly inspired by my peers; their insights and encouragement were invaluable throughout my journey. Additionally, my mentors played a significant role in shaping my academic path, offering guidance, knowledge, and encouragement that helped me navigate the complexities of my research.
3. What aspects of your study did you find most valuable? Why?
I found the opportunities to interact with principal investigators and scientists both within and outside NDWRH to be the most valuable and enjoyable aspects of my study. These interactions broadened my horizons beyond my specific research focus, enabling me to participate in several collaborations and learn new techniques. This exposure not only enriched my knowledge but also enhanced my ability to think critically and creatively in my work.
4. Have there been any particular projects or experiences that have helped influence your career path?
Yes, studying the broad aspects of mitochondrial biology has been instrumental in shaping my career path, as it allowed me to apply my knowledge across various research fields. Additionally, networking opportunities have played a crucial role in my journey, helping me secure multiple job positions. These experiences not only deepened my expertise but also expanded my professional connections, paving the way for future collaborations and career growth.
5. What is your current position, and how has your education contributed to your success?
I am currently a postdoctoral research scientist at the University of Oxford, specifically at the Target Discovery Institute, where I lead high-throughput CRISPR-Cas9 and various arrayed screening projects. My education has played a crucial role in my success, particularly the experience I gained while designing and leading my own projects and utilizing high-content imaging at the NDWRH.
This background has equipped me with the skills to effectively navigate complex research challenges and contribute significantly to my current work in target discovery.
6. What are your career goals?
In the short term, my focus is on writing successful grant applications that integrate cancer biology with my expertise in mitochondrial biology, allowing me to establish my own line of research.
In the long term, my goal is to lead my own research group, where I can further explore these intersections and mentor the next generation of scientists.
7. Do you have any advice for current students or those considering a career in women’s & reproductive health?
My advice for current students or those considering a career in women’s and reproductive health is to take full advantage of the knowledge around you.
The NDWRH is filled with amazing researchers, so don’t hesitate to ask questions and engage with them. Building relationships and seeking guidance can significantly enhance your learning experience and open doors to valuable opportunities in your field.
8. Do you have a surprising or interesting hobbies or achievements outside of your career?
One of my most interesting achievements outside of my career is that I took up boxing in the past few years and even participated in a charity boxing match to raise funds for the Lily Foundation, a small charity that supported my DPhil and first postdoctoral project.
Getting into the ring in front of nearly 400 people was nerve-wracking, but I truly enjoyed the experience. It not only challenged me physically but also allowed me to give back to a cause that has been instrumental in my journey.
To Find out more
We invite you to explore more of our alumni stories and discover how our postgraduate programmes continue to shape leaders in women’s and reproductive health. To learn more about our courses and how you can join this thriving community, visit our Alumni page and explore our Postgraduate programmes.