- PI Group: Prof Helen Townley
I am a DPhil candidate at Nuffield Department of Women’s and Reproductive Health, University of Oxford, supervised by Prof. Helen Townley. My main lab is based in the Advanced Technology of Institute building at Begbroke Science Park.
My DPhil research is mainly focused on developing an effective therapeutic platform which is able to target the paediatric tumours in an active manner. For a couple of years, I have been working on some natural products with the hope that we could understand their perceptive behaviours in promoting the cancer cell death. By the end of Trinity term in 2021, I’ve managed to find out the mode of antitumour mechanism of sesquiterpene lactones towards rhabdomyosarcoma cells. In the upcoming research, the antitumour agents will be encapsulated in the nanoparticles to enhance their therapeutic efficacies as well as to reduce the side effects in the clinical application. I am very interested in synthesising the lipid-based nanoparticles that are directed by some specific receptors on the surface of tumours and also controlled by the external environment.
Prior to the DPhil study, I have obtained a Master’s degree from Uppsala University, Sweden.
Mechanism of Action of the Sesquiterpene Compound Helenalin in Rhabdomyosarcoma Cells
Mun H. and Townley HE., (2021), Pharmaceuticals, 14, 1258 - 1258
Nanoparticle Delivery of siRNAs in Epithelial Ovarian Cancer Treatment
Mun H., (2021), Acta Scientific Cancer Biology
Nanoencapsulation of Plant Volatile Organic Compounds to Improve Their Biological Activities.
Mun H. and Townley HE., (2021), Planta Med, 87, 236 - 251