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PROJECT TITLE

Women’s health after complicated pregnancy: analysis of English population data to describe current practice and opportunities prevent cardiometabolic complications.


SUPERVISORS

Prof Mark Woodward

Dr Sanne Peters

Dr Jane Hirst


DESCRIPTION OF PROJECT

Medical disorders of pregnancy, specifically hypertensive disorders (preeclampsia, eclampsia and gestational hypertension) and gestational diabetes mellitus, greatly increase chances of developing longer-term cardiometabolic complications in the mother. Given the rise in prevalence of noncommunicable diseases (NCDs) worldwide, and the cost of these conditions to the NHS and other health systems, prevention strategies targeted to high-risk women have the potential to improve health and longevity in society. Whilst many medical societies and the WHO have recognised this increased risk, currently there is little evidence to guide screening frequency or advice for women in the months and years after birth. This project seeks to use routinely collected primary data from GP practices in the UK to describe the pattern of morbidity following complicated pregnancies, document the pattern of current screening practices for blood pressure, hypercholesterolaemia and hyperglycaemia performed in these women and assess health care for the primary and secondary prevention of cardiometabolic conditions. The first aim will be to compare care delivered to and consumed by women with adverse pregnancies, to women without adverse pregnancies. The second question will then be to assess the association between adverse pregnancy outcomes and the risk of cardiometabolic conditions. Third will be to assess the association between variation in health care delivery and consumption and the risk of cardiometabolic conditions. The project will involve working closely with epidemiologists and clinicians with expertise in women’s health, cardiovascular disease and gender differences in access to health care. The position will be based at The George Institute for Global Health, Oxford, as part of the portfolio of projects in the Institute’s Global Women’s Health Program.

 

TRAINING OPPORTUNITIES

This applicant will develop skills in big data analytics, specifically with the CPRD data set which is a linked system including data from GP practices, hospitals, disease registries and death certificates involving, overall, several millions of subjects during a period of over 15 years . The applicant will develop advanced statistical skills using STATA or R. They will also develop skills in systematic reviews and meta-aalysis, health policy analysis, academic writing and presentation. The applicant will directly work and collaborate with a multidisciplinary team of epidemiologists, statistician, and clinicians with strong experience and expertise in the field and will have access to the range of courses and training opportunities available through the University of Oxford. Furthermore, the applicant will be involved in the George Institute’s Global Women’s Health Program, which provides access to broader training and development opportunities, as well as exposure to international collaborators and data.

 

FUNDING INFORMATION

There is currently no funding allocated to this project.