Secondary hypertension: An update on the diagnosis and localisation of a pheochromocytoma or paraganglioma.

Siddiqui N., Daya R., Seedat F., Bulbulia S., Bayat Z.

Most cases of hypertension are because of essential hypertension, however 5% - 15% of cases can be a result of a secondary cause. In this article, we focus on the endocrine causes of secondary hypertension with a particular focus on pheochromocytomas (PCCs) and paragangliomas (PGLs). Around 15 endocrine disorders can initially present with hypertension. Amongst those PCCs and PGLs are rare but potentially life-threatening causes. An early diagnosis and timely referral can be life-saving. Herein, we present an approach for screening and diagnosis of these patients and focus on the importance of genetic testing.

DOI

10.4102/safp.v63i1.5277

Type

Journal article

Publication Date

2021-07-14T00:00:00+00:00

Volume

63

Pages

e1 - e6

Keywords

endocrine, metanephrines, normetanephrines, paraganglioma, pheochromocytoma, screening, secondary hypertension, succinate dehydrogenase, Adrenal Gland Neoplasms, Genetic Testing, Humans, Hypertension, Paraganglioma, Pheochromocytoma

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