Rethinking the application of nanoparticles in women's reproductive health and assisted reproduction.

Davis EH., Jones C., Coward K.

Nanoparticles and nanotechnology may present opportunities to revolutionize the prevention, treatment and diagnosis of a range of reproductive health conditions in women. These technologies are also used to improve outcomes of assisted reproductive technology. We highlight a range of these potential clinical uses of nanoparticles for polycystic ovary syndrome, endometriosis, uterine fibroids and sexually transmitted infections, considering in vitro and in vivo studies along with clinical trials. In addition, we discuss applications of nanoparticles in assisted reproductive technology, including sperm loading, gamete and embryo preservation and preventing preterm birth. Finally, we present some of the concerns associated with the medical use of nanoparticles, identifying routes for further exploration before nanoparticles can be applied to women's reproductive health in the clinic.

DOI

10.2217/nnm-2023-0346

Type

Journal article

Publication Date

2024-01-01T00:00:00+00:00

Volume

19

Pages

1231 - 1251

Total pages

20

Keywords

assisted reproductive technology, endometriosis, nanoparticles, polycystic ovary syndrome, sexually transmitted infections, uterine fibroids, women’s reproductive health, Humans, Female, Nanoparticles, Reproductive Health, Reproductive Techniques, Assisted, Women's Health, Polycystic Ovary Syndrome, Animals, Endometriosis, Pregnancy, Leiomyoma, Nanomedicine, Sexually Transmitted Diseases

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