COGENT: evaluating the consistency of gene co-expression networks.

Bozhilova LV., Pardo-Diaz J., Reinert G., Deane CM.

SUMMARY: Gene co-expression networks can be constructed in multiple different ways, both in the use of different measures of co-expression, and in the thresholds applied to the calculated co-expression values, from any given dataset. It is often not clear which co-expression network construction method should be preferred. COGENT provides a set of tools designed to aid the choice of network construction method without the need for any external validation data. AVAILABILITY AND IMPLEMENTATION: https://github.com/lbozhilova/COGENT. SUPPLEMENTARY INFORMATION: Supplementary information is available at Bioinformatics online.

DOI

10.1093/bioinformatics/btaa787

Type

Journal article

Publication Date

2021-07-27T00:00:00+00:00

Volume

37

Pages

1928 - 1929

Total pages

1

Keywords

Diagnostic Tests, Routine, Gene Expression, Gene Regulatory Networks, Software

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