{ "items": [ "\n\n
Our research focuses on the use of nanoparticles in cancer for therapy, imaging or drug delivery.
\n \n\n \n \nAssisted Reproductive Technology (ART) research seeks to shed light on the factors responsible for reproductive failure. We are also actively engaged in efforts to improve infertility treatments, such as in vitro fertilisation (IVF). Our work aims to simplify treatments and reduce risks, increase success rates and lower costs.
\n \n\n \n \nOur research explores sperm development, structure and function. Our overarching aim is to improve our understanding of the processes of sperm formation and function using a variety of laboratory techniques and models.
\n \n\n \n \nOur research focusses on understanding the intricate and complex mechanisms that regulate oocyte and follicle development in health and disease. The overarching goal is to develop new fertility treatments and fertility preservation methods for girls and women.
\n \n\n \n \nThis research examines how we modulate Mitochondrial quality control as an alternative to high profile Mitochondrial donation. This will enable families with Mitochondrial disease to have healthy children.
\n \n\n \n \nPre-eclampsia affects 5% of pregnant women, usually during the second half of pregnancy (from around 20 weeks) or soon after their baby is delivered. It is associated with significant problems in the mother and the baby. Our research examines the molecular mechanisms of pre-eclampsia and explores if we can predict and prevent this disease.
\n \n\n \n \nEvaluating neurodevelopment in different cultural settings is an integral component of early child development and is essential for observational and interventional studies focused on the first 1000 days of life.
\n \n\n \n \nOur work focuses on the pre pregnancy risk factors that pre dispose a complicated pregnancy (such as pre term babies, pre eclampsia or miscarriage)
\n \n\n \n \nOur work aims to optimise pain relief and quality of life for women with chronic pain by improving our understanding of the mechanisms generating pain in women and the interaction between hormones and pain.
\n \n\n \n \nOvarian cancer is one of the most lethal gynaecological malignancies predominantly because of late presentation and chemotherapy resistance. Recent advances in single cell RNA sequencing and DNA sequencing have made it possible to obtain unprecedented insights into tumour biology. Our lab has developed sequencing strategies and analysis algorithms to accelerate the mechanistic understanding of ovarian cancer initiation, progression and chemotherapy resistance. The use of these technologies and our access to patients recruited in clinical research studies provide exciting opportunities for addressing key questions in ovarian cancer such as a) understanding the cell of origin of ovarian cancer, b) characterising the tumour initiating cells in minimal residual disease and c) understanding T cell immune responses against ovarian cancer initiation and progression.
\n \n\n \n \nAn International Fetal and Newborn Growth Consortium dedicated to improving perinatal health through the development of new fetal and newborn growth standards, providing tools for the continuity of care from conception to 5 years of age.
\n \n\n \n \nThe Oxford Maternal & Perinatal Health Institute (OMPHI) works alongside Nuffield Department of Women's & Reproductive Health - bringing together world experts to resolve priority maternal and perinatal health problems on a global scale.
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